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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERT All Species: 21.21
Human Site: T765 Identified Species: 38.89
UniProt: O14746 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14746 NP_937983.2 1132 126997 T765 A F K S H V S T L T D L Q P Y
Chimpanzee Pan troglodytes XP_001141663 1135 126922 T768 L L C R Q V S T L T D L Q P Y
Rhesus Macaque Macaca mulatta XP_001096904 1132 126842 T765 T F K S H V S T L T D L Q P Y
Dog Lupus familis XP_851664 1092 121456 T755 A F K R H V S T F A D L Q P Y
Cat Felis silvestris
Mouse Mus musculus O70372 1122 127960 T756 S F R R Q V T T L S D L Q P Y
Rat Rattus norvegicus Q673L6 1125 126915 T756 S F R R Q V S T L S D L Q P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026178 1346 155264 T980 L Y K R H V S T F E D F I P D
Frog Xenopus laevis NP_001079102 1191 137998 E825 S F K R H V S E L A D V L P N
Zebra Danio Brachydanio rerio NP_001077335 1098 125968 A735 R K R F C T K A E M S E P L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781093 1312 150053 E953 S H R H V T T E L S S F H R Q
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001105870 1188 135970 V816 I Y R F D S N V S I S N G D N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_197187 1123 130561 K742 K I L V S S D K N S N F S R F
Baker's Yeast Sacchar. cerevisiae Q06163 884 102645 F557 A L K N E N G F F V R S Q Y F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 95.8 70.3 N.A. 63.3 63.3 N.A. N.A. 45.2 42.9 32.8 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 97.9 97.4 77.5 N.A. 74 73.5 N.A. N.A. 58.2 60.1 50.8 N.A. N.A. N.A. N.A. 42
P-Site Identity: 100 66.6 93.3 80 N.A. 60 66.6 N.A. N.A. 46.6 53.3 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 66.6 93.3 80 N.A. 86.6 86.6 N.A. N.A. 53.3 66.6 6.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. 24.7 N.A. 24.8 20.7 N.A.
Protein Similarity: N.A. 40.4 N.A. 42.6 36.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 20 N.A.
P-Site Similarity: N.A. 20 N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 0 0 0 0 0 8 0 16 0 0 0 0 0 % A
% Cys: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 0 0 0 62 0 0 8 8 % D
% Glu: 0 0 0 0 8 0 0 16 8 8 0 8 0 0 0 % E
% Phe: 0 47 0 16 0 0 0 8 24 0 0 24 0 0 16 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % G
% His: 0 8 0 8 39 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 0 8 0 0 8 0 0 % I
% Lys: 8 8 47 0 0 0 8 8 0 0 0 0 0 0 0 % K
% Leu: 16 16 8 0 0 0 0 0 54 0 0 47 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 8 0 8 0 8 8 0 0 24 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 62 0 % P
% Gln: 0 0 0 0 24 0 0 0 0 0 0 0 54 0 8 % Q
% Arg: 8 0 39 47 0 0 0 0 0 0 8 0 0 16 0 % R
% Ser: 31 0 0 16 8 16 54 0 8 31 24 8 8 0 0 % S
% Thr: 8 0 0 0 0 16 16 54 0 24 0 0 0 0 0 % T
% Val: 0 0 0 8 8 62 0 8 0 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 0 0 0 0 0 0 0 0 0 0 8 47 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _